Long-term Trend in Prostate Cancer Mortality in Turkey
Dilek Toprak1 and Nurhan Doğan2
1Department of Family Medicine, Faculty of Medicine, Bezmialem Foundation University, İstanbul, Turkey; 2Department of Biostatistics and Medical Informatics, Faculty of Medicine, Afyonkarahisar Health Sciences University, Afyonkarahisar, Turkey
Abstract: The main objective of this study was to analyze the mortality trends of prostate cancer in Turkey between the years 1987-2008. The age-standardized mortality rates (per 100,000) were calculated using the direct method, according to the World standard population. Temporal trends were assessed using the joinpoint regression. Average annual percent change (AAPC), anual percent change (APC), and a 95% confidence interval (CI) was calculated. During the period, the average annual age-standardized mortality rate (ASR) being 3.86 per 100,000 male. In the last five years, while significant decreases observed under the age of 65, there were also significant increases in the 65 and over age group. In this period, the biggest significant increase was in the over the age of 75 (AAPC=10.6, 95%CI=1.3 to 20.9). Increasing survival and an aging population have led more men to die from prostate cancer especially in older ages.
Keywords: Prostate cancer, Mortality, Joinpoint regression analysis.