Obtention of Scaffolds for Grafts on Human Skin with PLA-Nano fibers and Cinnamon Oil-Lanoline Emulsions

Authors

  • Leyre Marqués Arribas Universitat Politècnica de Catalunya, Terrassa, Spain
  • Paula Cota Carrera Universitat Politècnica de Catalunya, Terrassa, Spain
  • Francisco Cano "Institute of Textile Research and Industrial Cooperation of Terrassa-INTEXTER, Universitat Politècnica de Catalunya, Colom 15, 08222 Terrassa, Spain" & "Department of Materials Science and Engineering, Universitat Politècnica de Catalunya, Colom 1, 08222 Terrassa, Spain"
  • Meritxell Martí Gelabert "Institute of Textile Research and Industrial Cooperation of Terrassa-INTEXTER, Universitat Politècnica de Catalunya, Colom 15, 08222 Terrassa, Spain" & "Department of Materials Science and Engineering, Universitat Politècnica de Catalunya, Colom 1, 08222 Terrassa, Spain"
  • Alba Martínez Institute of Textile Research and Industrial Cooperation of Terrassa-INTEXTER, Universitat Politècnica de Catalunya, Colom 15, 08222 Terrassa, Spain
  • Manuel José Lis Arias Institute of Textile Research and Industrial Cooperation of Terrassa-INTEXTER, Universitat Politècnica de Catalunya, Colom 15, 08222 Terrassa, Spain

DOI:

https://doi.org/10.12974/2311-8717.2024.12.05

Keywords:

Electrospinning, Scaffolds, Cinnamon essential oil, PLA, Lanoline

Abstract

The interest in tissue engineering is growing in the scientific and medical communities, as it can solve actual problems regarding donor tissues, wound healing and drug delivery systems. Nanofibers are gaining relevance in this topic thanks to their excellent mechanical properties and similarities concerning the human skin.

This project has explored how combining the nanofibers’ membranes created of PLA, made by electrospinning, with a dissolution of lanoline and cinnamon essential oil not only imitates the human skin, as it was demonstrated in a later project, but also obtains an antibacterial character. Analytical techniques such as a spectrophotometer, an electrokinetic analyzer, a scanning electron microscope, a Fourier transform infrared spectroscope, and an optical tensiometer were employed.

Results confirmed successful integration and migration of the cinnamon oil, with antibacterial efficacy achieved against specific bacterial strains, as hypothesized. Notably, scaffolds composed of seven layers exhibited migration behavior closely aligned with theoretical expectations.

References

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Published

2024-12-30

How to Cite

Arribas, L. M. ., Carrera, P. C. ., Cano, F. ., Gelabert, M. M. ., Martínez, A. ., & Lis Arias, M. J. . (2024). Obtention of Scaffolds for Grafts on Human Skin with PLA-Nano fibers and Cinnamon Oil-Lanoline Emulsions. Journal of Composites and Biodegradable Polymers, 12, 41–51. https://doi.org/10.12974/2311-8717.2024.12.05

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