Development of Dextran Coated Zinc Oxide Nanoparticles with Antimicrobial Properties

Authors

  • Liliana Ghegoiu National Institute of Materials Physics, Atomistilor Street, No. 405A, P.O. Box MG 07, 077125 Magurele, Romania
  • Daniela Predoi National Institute of Materials Physics, Atomistilor Street, No. 405A, P.O. Box MG 07, 077125 Magurele, Romania
  • Simona Liliana Iconaru National Institute of Materials Physics, Atomistilor Street, No. 405A, P.O. Box MG 07, 077125 Magurele, Romania
  • Steluta Carmen Ciobanu National Institute of Materials Physics, Atomistilor Street, No. 405A, P.O. Box MG 07, 077125 Magurele, Romania
  • Roxana Trusca National Centre for Micro and Nanomaterials, University Politehnica of Bucharest, 060042 Bucharest, Romania
  • Mikael Motelica-Heino Department of Civil Engineering and Environment, Université d’Orléans, ISTO, UMR 7327 CNRS, 1A Rue de la Férollerie, 45071 Orléans, France
  • Monica Luminita Badea University of Agronomic Sciences and Veterinary Medicine Bucharest, Faculty of Horticulture, Bucharest, Bd Mărăsti no 59, sector 1, code 011464 Bucharest, Romania
  • Teodora-France Stefanescu C.A. Rosetti Highschool, Giuseppe Garibaldi Street No. 11, 014192Bucharest, Romania

DOI:

https://doi.org/10.12974/2311-8717.2024.12.01

Keywords:

Zinc oxide, Nanoparticles, Dextran, Antimicrobial properties

Abstract

Dextran coated zinc oxide nanoparticles with various zinc concentration have been developed in this study. Various characterization techniques were used in order to study the physical-chemical properties of the obtained samples. The structure of the samples was investigated using X-Ray diffraction (XRD), while the morphology was studied by scanning electron microscopy (SEM). Information regarding the porosity of the samples were obtained with the aid of Brunauer-Emmett-Teller (BET) method. The results of the physico-chemical characterization depicted the obtaining of a nanocomposite with homogenous and uniform morphology. Furthermore, the antimicrobial activity of the samples was also investigated against Gram-positive bacterial strains (Staphylococcus aureus 0364, Enterococcus faecalis ATCC 29212 and Bacillus subtilis), Gram-negative bacterial strains (Pseudomonas aeruginosa 1397, Escherichia Coli ATCC 259220 and against fungal strain Candida albicans ATCC 10231. The results of the antimicrobial assay showed that the nanocomposites exhibited good inhibitory effects against all the tested microorganisms making them suitable candidates for the further development of antimicrobial agents for biomedical applications.

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Published

2024-04-17

How to Cite

Ghegoiu, L. ., Predoi, D. ., Iconaru, S. L. ., Ciobanu, S. C. ., Trusca, R. ., Motelica-Heino, M. ., Badea, M. L. ., & Stefanescu, T.-F. . (2024). Development of Dextran Coated Zinc Oxide Nanoparticles with Antimicrobial Properties. Journal of Composites and Biodegradable Polymers, 12, 1–6. https://doi.org/10.12974/2311-8717.2024.12.01

Issue

Vol. 12 (2024)

Section

Articles